Course Offerings: Waterloo

Discussion of specialized topics related to the research interests of the members of the Centre. For example, recent offerings have included: Metalloproteins and Metalloenzymes; Heme Proteins; Chemistry of Enzymatic Reaction Mechanisms; Peptides – Synthesis, Structure and Function; Food Enzymology; Advanced Microbial Physicology; NMR in Biological Systems. This course covers the basics of biomolecular NMR spectroscopy and its application to protein and nucleic acid structure ...

The objective of this course is to provide an introduction to strategies for design of drug candidates, including structure-based and ligand-based drug discovery. It builds upon molecular modelling principles introduced in CHEM 340, and will apply them to specific problems in drug design. Specific topics include molecular modelling, molecular dynamics using molecular mechanics principles, molecular docking and virtual screening of drug molecules to target proteins, computational analysis of ...

This reading course provides an introduction to Quantum Molecular Dynamics approaches and their applications. A review of essential concepts of statistical mechanics will first be covered and the Feynman path integral formulation of quantum statistical mechanics will be introduced. Simulation techniques such as path integral Monte Carlo and path integral molecular dynamics will be discussed and illustrated with applications to quantum fluids, the spectroscopy of quantum clusters, the ...

This course provides an overview of laser fundamentals and the application of ultrashort optical and electron pulses in femtosecond pump-probe methods with emphasis on ultrafast structural dynamics. FORMAT OF LECTURES: Most lectures will be delivered in-person, with some exceptions delivered remotely or asynchronously. LEARNING OBJECTIVES: -Understand the basics of light propagation of in vacuum and dielectric materials. -Understand basic conditions for lasing: ...

Chemistry 766: Organic Spectroscopy is a graduate-level discussion on the use of spectroscopic techniques in organic chemistry. This course will focus specifically on the use of spectroscopic data for the identification and structural elucidation of organic molecules. Students will learn to effectively use a combination of datasets, consisting of mass spectroscopy (MS), infrared (IR) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy, for correctly identifying ...

Basic definitions: Monomers, polymers, polymerization reactions. Polymer structure, nomenclature. Molecular weight distributions and average molecular weights. Chain conformations: End-to-end distance, radius of gyration, molecular dimensions, excluded volume. Molecular weight measurements: Colligative properties, osmometry, light scattering, viscosity, gel permeation chromatography. Step-growth polymerization. Types of reactions. Reactivity, kinetics. ...

The objectives of the CHEM 784(0) requirement are to encourage MSc students to learn to use scientific literature at an early stage of their program, to stimulate in-depth thinking about the basis of their thesis research, and to develop their interpersonal and written communication skills. The goal of CHEM 784(0) is the construction of a written scientific literature review that focuses specifically on the thesis research topic of the individual student. Through this process, ...

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Introduction to basic principles of the common tools used for materials research and nanosciences; hands-on training of sample preparation, use and operation as well as data analysis involving common nanotool instrument systems, including light microscopy, scanning electron microscopy and related techniques, X-ray diffraction, optical spectroscopy and/or electron spectroscopy, and atomic force microscopy. ...

Organic Materials Synthesis will familiarize students with modern techniques that are used to synthesize organic electronic materials (conjugated molecules and polymers). Methods to be introduced include Pd-catalyzed cross-coupling reactions (Suzuki, Stille, Sonagashira etc.), other catalytic and stoichiometric techniques (Yamamoto, Kumada, Gilch etc.), oxidative polymerization (chemical and electrochemical) and C-H bond activation strategies. The methods will be discussed within the context ...