Course Offerings: Waterloo

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Antibiotics play essential roles in all branches of healthcare, and the emergence and spread of antibiotic-resistant bacteria pose a significant risk to public health. This course will focus on understanding the biochemical rationale behind how various classes of antibiotics target key bacterial pathways. It will also explore the complexities of antimicrobial resistance mechanisms and practical approaches to overcome them. Advances in antibiotic discovery and alternative therapies like ...

In the winter 2025 term the focus of the course will be electronic structure theory and some discussions of vibrational problems and coupled electronic-nuclear motion (non-adiabatic systems). The course will cover a description of the basic electronic structure problem introducing an atomic orbital basis set, Slater determinants and the Slater-Condon rules. Then we will cover Hartree-Fock theory in fair detail, and briefly discuss density functional theory, in analogy to Hartree-Fock.  We ...

This course is inspired by recent experimental advances in the field of solid-state quantum information processing (QIP), especially electron spin qubits realized in semiconductor nanostructures known as quantum dots (“artificial atoms”). It begins by covering the fundamentals of spin and angular momentum, QIP, semiconductor physics, quantum transport, and quantum dots. The course aims to equip students to fully comprehend the research literature in the field of semiconductor spin qubits ...

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Atomic and molecular clusters constitute intermediates between molecules, with clearly defined quantum states, and condensed matter where these states form bands or continua. As such, the study of clusters can be viewed as a means of unravelling the evolution of bulk properties from those of the constituent atoms/molecules. Interestingly, owing to the high ratio of surface atoms to bulk atoms, there are many analogies between the chemistry and physics of clusters and of solid surfaces. For ...

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This graduate level course will familiarize students with the principles of organometallic chemistry by covering various stoichiometric and catalytic organometallic reactions. An introduction to the mechanisms of organometallic reactions, and the importance of organometallic complexes in metal-promoted bond-forming and bond-breaking processes will be illustrated with examples of applications in organic synthesis. ...

The glassy state and the glass transition: Phenomenology. Free volume, thermodynamic and kinetic theories. Plasticization, molecular weight, cross-linking effects, blending. Structure-property correlations. Dynamic mechanical properties, glassy state relaxations. Rubber elasticity: Phenomenology, stress-strain measurements. Quantitative treatment of rubber elasticity: thermodynamic and statistical approaches. Affine and phantom network deformation. Cross-linking, swelling, ...

Prerequisites: Chem 731 Biomolecular NMR Spectroscopy and two terms of Calculus at UG level (for example, Math 127/128 at UW). This course covers the advanced theory of NMR spectroscopy, including energy level, vector model, density matrix and product operator formalism. Among the topics discussed are: Basics of NMR spectroscopy Spectrometer hardware Energy level description of NMR spectroscopy The vector model in ...

This graduate course will address the underlying principles of enzymatic catalysis (with examples) along with discussion of techniques that are applied to this area. This course will focus on the protein itself and how its structure contributes to catalysis. Subtopics will include protein dynamics, electrostatic potential, active-site geometry and transition state stabilization among other factors that contribute to enzyme catalysis and substrate selectivity. The chemical mechanism of ...

Introduction to basic principles of the common tools used for materials research and nanosciences; hands-on training of sample preparation, use and operation as well as data analysis involving common nanotool instrument systems, including light microscopy, scanning electron microscopy and related techniques, X-ray diffraction, optical spectroscopy and/or electron spectroscopy, and atomic force microscopy. Week ...

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