CHEM 750/7500-01 - Advanced Analytical Chemistry

Semester: Winter 2022

Professor: K. Ghandi | Discipline: Physical | Campus: Guelph


The purpose of the course is to introduce chemical and biochemical sensors, elemental analysis techniques that has not been examined in typical undergraduate analytical chemistry courses, and exotic particle accelerator based analytical probes. The course will address some new, exciting frontiers in analytical chemistry, how research activities in the field relate to other scientific endeavors and disciplines, and the how analytical chemistry relates to applications and supports the progress of future health, material and energy technologies.
The graduate course includes completion of term papers and presentations. An undergraduate background in physical chemistry or physics and analytical chemistry is expected. Students with an undergraduate degree in engineering should consult with the instructor before registering.

The following is the proposed chronologic list of subjects:

  1. Chemical and biosensors
  2. Elemental analysis
  3. Particle accelerator based analytical probes
  4. Analytical interstellar chemistry
    If time permits the following will also be discussed
  5. Lasers in analytical chemistry
  6. Analytical probes of radiation therapy
  7. Selected topics in use of analytical techniques for applications in nuclear energy


Reading material will be based on research articles, review articles and some book chapters and will be emailed to class or if both Waterloo and Guelph students have access to courselink they will be posted on courselink.



The proposed marking scheme is as follows. It will be discussed and finalized during the first week of class though:

Assignments 40%

Final Exam (take home) 20%: Deadline: Second day of exam period.


Term Project and Presentation 40%

PhD students: 3 projects and presentations. MSc students: 2 project and presentation. Undergrad students: 1 project and presentation. Each project includes a review article and presenting that review to class. The review can be on any subject related to analytical chemistry. Subjects should be selected and confirmed by instructor on or before Tuesday January 28, 2020. You need to first find the most recent review article and then write your own review of all research articles related to that subject published after the review article.

  • Each project is a review article on a subject of your interest related to analytical chemistry. There is no format limitation or space limit. You need to decide about your subject of interest. Anyone that selects a subject will let me know and I announce it so that the rest would not select that subject. You will find the most recent review article on that subject and your review will be a summary of that review article and all research papers published after that review article.
  • You will be marked based on quality of your review (not missing published research articles is an important criteria; also harmonious writing rather than a scattered report is another important criteria) and your presentation.
  • Your presentation to class will be marked by all class (including me). The students are asked to provide instructive feedbacks also to the instructor. The instructor will summarize and share the feedbacks without names with the presenter. Total project mark is 30 percent for review papers (in word) and 10 percent on presentations.
  • Presentation to class marks: 2 for learning content (You also need to describe the concepts.). 2 for clarity. 2 for the degree of engaging presentation. 2 for answering questions. Each presentation is normally 20 minutes followed by questions.

All review papers should be sent to me via email in word format. It can be sent at any time before your presentation. However, the feedback to improve them (to get better marks) will be sent only to those that send me the papers a week before their presentation. It is in your benefit to send me your first draft as soon as possible during the semester since you won’t get mark for drafts, only on final version. This way you can receive feedback early on to improve your reviews.


  • Thu: 7:00 pm - 9:20 pm in MacN 101/EIT 2053

Office Hours