Course Offerings: Biochemistry

This graduate course will address the underlying principles of enzymatic catalysis (with examples) along with discussion of techniques that are applied to this area. This course will focus on the protein itself and how its structure contributes to catalysis. Subtopics will include protein dynamics, electrostatic potential, active-site geometry and transition state stabilization among other factors that contribute to enzyme catalysis and substrate selectivity. The chemical mechanism of ...

This course covers the basics of biomolecular NMR spectroscopy and its application to protein and nucleic acid structure determination. Among the topics discussed are: • Basics of NMR spectroscopy • Spectrometer hardware • Types of pulse sequences and their application • Extracting NMR parameters from spectra • Types and use of software for the analysis of NMR spectra and structure calculation/analysis • Preparation and writing of a ...

TBA ...

Course objective:  Understand the biochemical principles of drug action Overview of topics Introduction Pharmacodynamics: General principles of drug action Pharmacokinetics: Uptake, distribution, and elimination of drugs Pharmacology of nerve and muscle cells G protein-coupled receptors as drug targets Drugs that modulate nitric oxide signaling Eicosanoid mediators and related drugs Drugs ...

Advanced topics in toxicology will include oral presentations by students, faculty members, and guest lecturers. The emphasis will be on advanced concepts and techniques in toxicology research with particular relevance to mechanistic, molecular and interpretive toxicology. Pre-Requisite(s): N/A Restriction(s): Credit may be obtained for only one of TOX*6200/CHEM*731 or TOX*4200 Method of Delivery: On-line via Zoom on ...