Course Offerings: Biochemistry

CHEM 731/7310-01 - Antibiotics and Resistance

Semester: Winter 2025 Professor: D. Sychantha | Discipline: Biochemistry | Campus: Waterloo
Antibiotics play essential roles in all branches of healthcare, and the emergence and spread of antibiotic-resistant bacteria pose a significant risk to public health. This course will focus on understanding the biochemical rationale behind how various classes of antibiotics target key bacterial pathways. It will also explore the complexities of antimicrobial resistance mechanisms and practical approaches to overcome them. Advances in antibiotic discovery and alternative therapies like ...

CHEM 731/7310-02 - Nucleic Acid Chemistry

Semester: Winter 2025 Professor: D. O'Flaherty | Discipline: Biochemistry | Campus: Guelph
This course provides students with general and specific aspects of selected key areas in bio-organic chemistry with an emphasis on nucleic acids: Structure and reactivity of nucleosides(tides), nucleic acids (roughly 75-95 % of course material) Structure and reactivity of amino acids, peptides, proteins (roughly 5-25 % of course material) Part I: Development of nucleic acid chemistry, medicinal chemistry of nucleosides, heterocyclic assembly, synthetic ...

CHEM 737/7370 - Enzymes

Semester: Spring 2025 Professor: J. Honek | Discipline: Biochemistry | Campus: Waterloo
TBA ...

CHEM 731-7310-01 - Biomolecular NMR Spectroscopy of Proteins and Nucleic Acids

Semester: Fall 2024 Professor: T. Dieckmann | Discipline: Biochemistry | Campus: Waterloo
Discussion of specialized topics related to the research interests of the members of the Centre. For example, recent offerings have included: Metalloproteins and Metalloenzymes; Heme Proteins; Chemistry of Enzymatic Reaction Mechanisms; Peptides – Synthesis, Structure and Function; Food Enzymology; Advanced Microbial Physicology; NMR in Biological Systems. This course covers the basics of biomolecular NMR spectroscopy and its application to protein and nucleic acid structure ...

CHEM 731/7310-02 - Rational Drug Design

Semester: Fall 2024 Professor: S. Kalyaanamoorthy | Discipline: Biochemistry | Campus: Waterloo
The objective of this course is to provide an introduction to strategies for design of drug candidates, including structure-based and ligand-based drug discovery. It builds upon molecular modelling principles introduced in CHEM 340, and will apply them to specific problems in drug design. Specific topics include molecular modelling, molecular dynamics using molecular mechanics principles, molecular docking and virtual screening of drug molecules to target proteins, computational analysis of ...