Course Offerings: Biochemistry

This course covers the basics of biomolecular NMR spectroscopy and its application to protein and nucleic acid structure determination. Among the topics discussed are: • Basics of NMR spectroscopy • Spectrometer hardware • Types of pulse sequences and their application • Extracting NMR parameters from spectra • Types and use of software for the analysis of NMR spectra and structure calculation/analysis • Preparation and writing of a ...

TBA ...

TBA ...

This graduate course will address the underlying principles of enzymatic catalysis (with examples) along with discussion of techniques that are applied to this area. This course will focus on the protein itself and how its structure contributes to catalysis. Subtopics will include protein dynamics, electrostatic potential, active-site geometry and transition state stabilization among other factors that contribute to enzyme catalysis and substrate selectivity. The chemical mechanism of ...